Anesth Pain Med Search

CLOSE


Pediatric Anesthesia
Anesthesia and Pain Medicine 2008;3(4):322-326.
Published online October 30, 2008.
Study on optimum dose of remifentanil in a combined pediatric anesthesia with sevoflurane during inguinal minor surgery
Min Ho Ju, Mi Woon Kim, Sung Won Lee
Department of Anesthesiology and Pain Medicine, College of Medicine, Dongguk University, Gyeongju, Korea. swankim7@yahoo.co.kr
Abstract
BACKGROUND
Remifentanil can maintain hemodynamic stability in pediatric anesthesia. However, it is also known to frequently have hemodynamic adverse effects including hypotension and bradycardia when large doses are used. Therefore, we aimed to find the optimum dose of remifentanil that can minimize the hemodynamic changes when it is used in combination with sevoflurane in pediatric anesthesia.
METHODS
We studied 59 patients who were planned for under general anesthesia, aged between 2 and 8 years. They were randomly divided into two groups. The children in the Group S were anesthetized using sevoflurane 1 MAC and those in the Group R were given a combination of sevoflurane 0.5 MAC and remifentanil 0.1?0.2microg/kg/min. During anesthesia, the N2O was maintained at 50% in all subject children and the anesthesiologist recorded hemodynamic changes before, immediately after and at 5, 10, 15, 20, 25 and 30 minutes after tracheal intubation. The total dose of remifentanil administered during the anesthesia was recorded after the completion of the anesthesia.
RESULTS
There was no significant difference of blood pressure observed between the two groups. Significant difference of heart rate was observed in the Group R at 5, 10, 15, 20, 25 and 30 minutes after tracheal intubation as compared with the Group S. The average dosage of remifentanil administered during the surgery in the Group R was 0.121 +/- 0.057microg/kg/min.
CONCLUSIONS
In pediatric anesthesia, a combined administration of 0.5 MAC sevoflurane and remifentanil (0.12microg/kg/min) could achieve similar degree of the depth of anesthesia and hemodynamic stability as 1 MAC sevoflurane only.
Key Words: hemodynamic change, pediatric anesthesia, remifentanil, sevoflurane
TOOLS
Share :
Facebook Twitter Linked In Google+ Line it
METRICS Graph View
  • 1,015 View
  • 6 Download
Related articles in Anesth Pain Med


ABOUT
ARTICLE & TOPICS
Article category

Browse all articles >

Topics

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: apm@anesthesia.or.kr                

Copyright © 2024 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next