The relationship of serum creatinine and cardiac troponin I after off-pump coronary artery bypass graft surgery

Jung, Hwa Sung; Kim, Che Sun; Kim, Tae Yop

Search: Anesth Pain Med Search

CLOSE

Clinical Research

Cardiothoracic and Vascular Anesthesia

Anesthesia and Pain Medicine 2009;4(2):124-128.
Published online April 30, 2009.

The relationship of serum creatinine and cardiac troponin I after off-pump coronary artery bypass graft surgery

Hwa Sung Jung, Che Sun Kim, Tae Yop Kim

¹Department of Anesthesiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. pondkim@unitel.co.kr
²Department of Anesthesiology, GangNeung Asan Hospital, School of Medicine, University of Ulsan, Gangneung, Korea.
³Department of Anesthesiology and Pain Medicine, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, Masan, Korea.

Abstract

BACKGROUND
Renal dysfunction is an independent risk factor of cardiac dysfunction and one of common complications after cardiac surgery. This study was designed to evaluate the relationship between serum creatinine (s-Cr) and cardiac troponin I (cTnI) in off-pump coronary artery bypass graft surgery (OPCAB).
METHODS
Data, from 13 patients underwent OPCAB, were analyzed in prospective fashion. The levels of s-Cr and cTnI were evaluated before and after OPCAB. The correlations of s-Cr and TnI were analyzed in the patients with cardiac dysfunction assessed by low cardiac output or stroke volume at end of surgery.
RESULTS
Patients with preoperatively elevated s-Cr (female, > or =1.2 microg/L; male, > or =1.5microg/L) showed higher incidence of elevated s-Cr and elevated cTnI (> or =0.68microg/L) on arrival at intensive care unit (POD-0), postoperative 12 hours (POD-1) and postoperative 36 hours (POD-2) (P< 0.05). Patients with preoperatively elevated cTnI showed higher incidence of elevated cTnI at POD-0, POD-1 and POD-2 (P< 0.05). In 7 patients with low cardiac index (< 2.0 L/min/m2) or stroke volume index (<40 mL/beat/m2) at end of surgery, the increases of s-Cr and cTnI showed positive correlation at POD-0, POD-1 and POD-2 (correlation coefficient 0.818, 0.864 and 0.785, respectively).
CONCLUSIONS
The increases of s-Cr and cTnI showed positive correlation in low cardiac output after OPCAB. The results suggested that elevated s-Cr may be an independent predictor of elevated cTnI representing perioperative myocardial injury.

Key Words: creatinine, off-pump coronary artery bypass grafting surgery, troponin I

TOOLS

PDF Links
Full text via DOI
Download Citation

Share :

METRICS

1,383 View
29 Download

Related articles in Anesth Pain Med

The Effect of Diabetes Mellitus on Vasoconstrictor Requirement and Hemodynamic Parameters in Patients Undergoing Off Pump Coronary Artery Bypass Graft Surgery2006 July;1(1)

The Effects of Magnesium Infusion on Left Ventricular Stroke Work Index during off Pump Coronary Artery Bypass Grafting2007 July;2(3)

Effect of prophylactic continuous infusion of isosorbide dinitrate on myocardial protection and hemodynamics in patients undergoing off-pump coronary bypass surgery2009 April;4(2)

Resuscitated cardiac arrest caused by coronary artery spasm after coronary artery bypass grafting: A case report-2017 April;12(2)

ABOUT

ARTICLE & TOPICS

Article category

Browse all articles >

Topics

Browse all articles >

BROWSE ARTICLES

AUTHOR INFORMATION

Editorial Office: 101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128 Fax: +82-2-792-4089 E-mail: apm@anesthesia.or.kr