Remimazolam: pharmacological characteristics and clinical applications in anesthesiology
Kyung Mi Kim
Anesth Pain Med. 2022;17(1):1-11.   Published online 2022 Jan 20     DOI: https://doi.org/10.17085/apm.21115
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Journal of Clinical Anesthesia.2023; 86: 111077.     CrossRef
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Journal of Personalized Medicine.2023; 13(5): 789.     CrossRef
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Journal of Clinical Medicine.2023; 12(10): 3558.     CrossRef
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Scientific Reports.2023;[Epub]     CrossRef
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BMC Anesthesiology.2023;[Epub]     CrossRef
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Medicina.2023; 59(7): 1197.     CrossRef
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Journal of Clinical Anesthesia.2023; 90: 111223.     CrossRef
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Anesthesia and Pain Medicine.2023; 18(3): 252.     CrossRef
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British Journal of Anaesthesia.2023; 131(5): 914.     CrossRef
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Shingo Narumi, Yusuke Ishida, Sae Igarashi, Shunya Sekiguchi, Aya Kawachi, Mikiko Tomino
Clinical Case Reports.2023;[Epub]     CrossRef
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Scientific Reports.2023;[Epub]     CrossRef
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BMC Anesthesiology.2022;[Epub]     CrossRef
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