• Home
  • E-submission
  • Sitemap
  • Contact us
  • Search
  • Advanced Search
Anesth Pain Med Search

CLOSE

Clinical Research
Cardiothoracic and Vascular Anesthesia
Anesthesia and Pain Medicine 2007;2(3):132-136.
Published online July 31, 2007.
The Effects of Magnesium Infusion on Left Ventricular Stroke Work Index during off Pump Coronary Artery Bypass Grafting
Tae Gyun Kim, Young Jhoon Chin, Jong Hwan Lee, Seung Cheol Lee
Department of Anesthesia and Pain Medicine, College of Medicine, Dong- University, Busan, Korea. yjjin@dau.ac.kr
Abstract
BACKGROUND
The administration of magnesium provides cellular protection during ischemia, improves the contractile response of the stunned myocardium, increases the threshold for the electrical excitation of myocardial cells, presents arrhythmia, and reduces the level of reperfusion injury. It also causes a decrease in peripheral vascular resistance in association with a secondary increase in the cardiac index and improves the left ventricular stroke work index. The aim of this study was to verify characteristic effects of magnesium infusion during off pump coronary artery bypass grafting (OPCAB). METHODS: In a prospective double-lind trial, 17 patients undergoing OPCAB were randomly assigned to receive intravenous magnesium sulfate (n = 9) or a placebo (n = 8). The mean arterial pressure (MAP), pulmonary capillary wedge pressure (PCWP), heart rate (HR), cardiac index (CI), left ventricular stroke work index (LVSWI), right ventricular stroke work index (RVSWI), systemic vascular resistance (SVR) and pulmonary vascular resistance (PVR) were measured. RESULTS: MAP, PCWP, HR, CI, LWSWI, RVSWI, SVR, and PVR using the thermodilution method were not significantly different in both groups. Post operative arrhythmia occurred in 1 out of 9 patients after the administration of magnesium and in 1 out of 8 patients after infusing the placebo. CONCLUSIONS: The administration of magnesium does not affect the increase in LVSWI during OPCAB and does not decrease the incidence of post operative arrhythmia in the operating room period.
Key Words: arrhythmia, cardiac, index, left, ventricle, stroke, work
TOOLS
Share :
Facebook Twitter Linked In Google+ Line it
METRICS Graph View
  • 1,068 View
  • 7 Download
Related articles in Anesth Pain Med

The Effect of Diabetes Mellitus on Vasoconstrictor Requirement and Hemodynamic Parameters in Patients Undergoing Off Pump Coronary Artery Bypass Graft Surgery2006 July;1(1)

The relationship of serum creatinine and cardiac troponin I after off-pump coronary artery bypass graft surgery2009 April;4(2)

ABOUT
ARTICLE & TOPICS
Article category

Browse all articles >

Topics

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Editorial Office
101-3503, Lotte Castle President, 109 Mapo-daero, Mapo-gu, Seoul 04146, Korea
Tel: +82-2-792-5128    Fax: +82-2-792-4089    E-mail: apm@anesthesia.or.kr                

Copyright © 2024 by Korean Society of Anesthesiologists.

Developed in M2PI

Close layer
prev next