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Use of methylene blue in vasoplegic syndrome that developed during non-cardiac surgery - A case report -
Anesth Pain Med 2019;14(4):460-4
Published online October 31, 2019
© 2019 Korean Society of Neuroscience in Anesthesiology and Critical Care.

In Duk Oh , Eunsil Shin , Jong-Mi Jeon , Hyunho Woo , and Jeong-Hyun Choi
Department of Anesthesiology and Pain Medicine, Kyung Hee University College of Medicine, Seoul, Korea
Correspondence to: Jeong-Hyun Choi, M.D., Ph.D. Department of Anesthesiology and Pain Medicine, Kyung Hee University Hospital, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea Tel: 82-2-958-8589 Fax: 82-2-958-8580 E-mail: choikhang@gmail.com
ORCID https://orcid.org/0000-0003-1995-1220
Received October 10, 2018; Revised January 31, 2019; Accepted February 1, 2019.
cc This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Vasoplegic syndrome is an increasingly recognized disease in perioperative medicine and is characterized by severe hypotension, normal or elevated cardiac output, and decreased systemic vascular resistance. It occurs commonly after cardiopulmonary bypass but may also occur after other types of surgery.
Case: Vasoplegic syndrome developed in our patient during posterior lumbar interbody fusion because of administering nicardipine after phenylephrine. However, the blood pressure did not increase as expected despite simultaneous use of norepinephrine and vasopressin to increase the reduced systemic vascular resistance.
Conclusions: We present a case of vasoplegic syndrome that developed during posterior lumbar interbody fusion and was treated successfully with methylene blue.
Key Words : Methylene blue; Nicardipine; Vasoplegia.


October 2019, 14 (4)
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